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翁芸芳（Ueng, Yune-Fang）

翁芸芳個人生活照姓名：翁芸芳（Ueng, Yune-Fang）
職稱：研究員兼中醫藥基礎研究組組長
電話：2820-1999 轉6351、6361
E-mail：ueng@nricm.edu.tw

學歷:

國立台灣大學 醫學院 生物化學研究所 博士
高雄醫學院 藥學系 學士

主要經歷:
臺北醫學大學  兼任教授
國立陽明交通大學 藥物科學院、醫學院 兼任副教授
美國范德堡大學 醫學院 生化所暨分子毒理中心 博士後研究員
國立台灣大學 醫學院 毒理學研究所 博士後副研究員


其他經歷:
台灣毒物學會幹事　
台灣藥理學會藥理簡訊編輯委員　
台灣毒物學會會員　
台灣藥理學會會員
期刊編輯/諮詢編輯委員: J. Food Drug Anal.、Drug Metab. Pharmacokinet.

學術榮譽事項:
中華民國斐陶斐榮譽學會　
毒藥物防治學術獎座

專長:
藥物代謝，藥學 ，生化毒理學

研究簡介:
      藥物代謝酶在外來物包括天然物、藥物、環境污染物之生物活性及解毒作用中扮演重要角色。
研究主題在
(一)、探討天然物與藥物代謝酶之相互影響以評估產生藥物交互作用之可能性；
(二)、確認天然物之代謝產物並了解參與其代謝之人類藥物代謝酶。

期刊論文: 限所內研究人員(用Email)點選編輯點此編輯

      NCBI PubMed :  Yune-Fang Ueng (Please click!!)

 

Patent:

  1. 李文泰、蕭永基、翁芸芳，專利名稱: 二苯乙烯及苯并呋喃衍生物用於治療神經性疾病之用途 (專利權人: 衛生福利部國家中醫藥研究所，中華民國，發明第1644665號，專利權期間：2018年12月21日至2023年12月7日)

 

Publications:

Refereed Publications: h-index (文獻數量和引用次數的交集數; 使用Google Scholar): 37

  1. Ueng, Yune-Fang, Ju, Jr-Min, Tang, Hung-Chi, Lin, Jen-Kun, and Ueng, Tzuu-Huei*, Induction of monooxygenase activity by 3-methylcholanthrene in a tilapia hybrid. Proc. Natl. Sci. Council ROC, Part B 13: 184-191, 1989.
  2. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, Liu, Ying-Hsiu, Lin, Jen-Kun, and Lee, Sin-Che, Induction of monooxygenase activity by polychlorinated biphenyls and 3-methylcholanthrene in a tilapia hybrid. Proc. Natl. Sci. Council ROC, Part B 14: 201-208, 1990.
  3. Ueng, Tzuu-Huei*, Tasi, Jen-Ning, Ju, Jr-Min, Ueng, Yune-Fang, Iwasaki, Masahiko, and Guengerich, F. Peter, Effects of acetone administration on cytochrome P-450-dependent monooxygenases in hamster liver, kidney, and lung. Arch. Toxicol. 65: 45-51, 1991. (IF:5.901; citation: 20)
  4. Ueng, Tzuu-Huei* and Ueng, Yune-Fang, Induction of cytochrome P-450-dependent monooxygenases by isoniazid in hamster liver, kidney, and lung. J. Formosan Med. Assoc. 90: 723-730, 1991. (citation: 2)
  5. Liu, Tsung-Yun*, Cheng, S.-L., Ueng, Tzuu-Huei, Ueng, Yune-Fang, and Chi, Chin-Wen, Comparative analysis of aromatic DNA adducts in fish from polluted and unpolluted areas by 32P-postlabeling analysis. Bull. Environ. Contam. Toxicol. 47: 783-789, 1991. (citation:22)
  6. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, Chen, Ta-Liang, and Alvares, Alvito P., The relationship between induction of metallothionein and inhibition of monooxygenases by cadmium and lead. J. Chinese Biochem. Soc. 20: 87-98, 1991.
  7. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, and Park, San-Shin, Comparative induction of cytochrome P-450-dependent monooxygenases in the livers and gills of tilapia and carp. Aquat. Toxicol. 23: 49-64, 1992.
  8. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, Chen, Ta-Liang, Park, San-Shin, Iwasaki, Masahiko, and Guengerich, F. P., Induction of cytochrome P450-dependent monooxygenases in hamster tissues by fasting. Toxicol. Appl. Pharmacol. 119: 66-73, 1993. (SCI, IF:4.219; citation: 31; 29/93=31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  9. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, Tasi, Jen-Ning, Chao, I.-Chi, Chen, Ta-Liang, Park, Sang-Shin, Iwasaki, Masahiko, and Guengerich, F. Peter, Induction and inhibition of cytochrome P450-dependent monooxygenases in hamster tissues by ethanol. Toxicology 81: 145-154, 1993. (IF: 3.621; citation: 21)
  10. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, and Chou, Ming-Wu, Regioselective metabolism of benzo(a)pyrene and 7-chlorobenz(a)anthrene by fish liver microsomes. Toxicol. Lett. 70: 89-99, 1994. (IF: 3.262)
  11. Ueng, Tzuu-Huei*, Ueng, Yune-Fang, Chen, W., and Chou, Ming W., Regioselective and stereoselective metabolism of benzo(a)pyrene and 7-chlorobenz(a)anthracene by fish liver microsomes. Polycy. Aromat. Comp. 7: 107-114, 1994.
  12. Ueng, Yune-Fang, Liu, Tsung-Yun, and Ueng, Tzuu-Huei*, Induction of cytochrome P450 1A1 and monooxygenase activity in tilapia by sediment extract. Bull. Environ. Contam. Toxicol. 54: 60-67, 1995. (SCI; citation: 6)
  13. Ueng, Yune-Fang, Shimada, Tsutomo., Yamazaki, Hiroshi, and Guengerich, F. Peter*, Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes. Chem. Res. Toxicol. 8: 218-225, 1995. (SCI;IF: 3.278; citation: 195)
  14. Bauer, Eckhart, Guo, Zuyu., Ueng, Yune-Fang, Bell, L. Chastine, Zeldin, Darryl, and Guengerich, F. Peter*, Oxidation of benzo(a)pyrene by recombinant human cytochrome P450 enzymes. Chem. Res. Toxicol. 8: 136-142, 1995. (SCI;IF: 3.278; citation: 190)
  15. Gillam, Elizabeth M. J., Guo, Zuyu, Ueng, Yune-Fang, Yamazaki, Hiroshi, Cock, I., Reilly, P. E. B., Hooper, W. D., and Guengerich, F. Peter*, Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5’ modification, purification, spectral characterization, reconstitution conditions, and catalytic activities. Arch. Biochem. Biophys. 317: 374-384, 1995. (SCI;IF: 3.017; citation: 152)
  16. Yamazaki, Hiroshi, Ueng, Yune-Fang, Shimada, Tsutomu, and Guengerich, F. Peter*, Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH-cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates. Biochemistry 34: 8380-8389, 1995. (SCI;IF=3.015; citation: 132)
  17. Ueng, Yune-Fang, and Ueng, Tzuu-Huei*, Induction and purification of cytochrome P4501A1 from 3-methylcholanthrene-treated tilapia, Oreochromis niloticus X Oreochromis aureus. Arch. Biochem. Biophys. 322: 347-356, 1995. (SCI;IF: 3.017; citation: 23)
  18. Souček, Pavel, Martin, Martha V., Ueng, Yune-Fang, and Guengerich, F. Peter*, Identification of a common epitope near the conserved heme-binding peptide with antibodies raised against recombinant cytochrome P450 family 2 proteins. Biochemistry 34: 16013-16021, 1995. (SCI;IF=2.938; citation: 26)
  19. Tateishi, T., Krivoruk, Y., Ueng, Yune-Fang, Wood, A. J. J., Guengerich, F. Peter, and Wood, M.*, Identification of human liver cytochrome P450 3A4 as the enzyme responsible for fetanyl and sufentanil N-dealkylation. Anesthesia and Analgesia 82: 167-172, 1996. (SCI;IF=3.472; citation: 116)
  20. Yamazaki, Hiroshi, Nakano, M., Imai, Y., Ueng, Yune-Fang, Guengerich, F. Peter, and Shimada, Tsutomu.*, Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes. Arch. Biochem. Biophys. 325: 174-182, 1996. (SCI;IF: 3.017; citation: 129)
  21. Koehl, W., Amin, S., Staretz, M. E., Ueng, Yune-Fang, Yamazaki, Hiroshi, Tateishi, T., Guengerich, F. Peter, and Hecht, S. S.*, Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes. Cancer Res. 56: 316-324, 1996. (SCI;IF= 9.329; citation: 23)
  22. Guengerich, F. Peter*, Johnson, William W., Ueng, Yune-Fang, Yamazaki, Hiroshi, and Shimada, Tsutomu., Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer. Environ. Health Perspect. 104: 557-562, 1996. (SCI; citation: 100)
  23. Ueng, Yune-Fang, Liu, C., Li, C., Meng, Li-Ming, Hung, Y., and Ueng, Tzuu-Huei*, Effects of cadmium and environmental pollution on metallothionein and cytochrome P450 in tilapia. Bull. Environ. Contam. Toxicol. 57, 125-131, 1996. (SCI; citation: 25)
  24. Ingelman-Sundberg, Magnus, Hagbjork, A. L., Ueng, Yune-Fang, Yamazaki, Hiroshi, and Guengerich, F. Peter*, High rates of substrate hydroxylation by human cytochrome P450 3A4 in reconstituted membranous vesicles: influence of membrane charge. Biochem. Biophys. Res. Comm. 221: 318-322, 1996. (SCI; citation: 52)
  25. Shimada, Tsutomu*, Yamazaki, Hiroshi, Mimura, M., Wakamiya, N., Ueng, Yune-Fang, Guengerich, F. Peter, and Inui, Y., Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal livers and adult lungs. Drug Metab. Dispos. 24: 515-522, 1996. (SCI;IF= 3.354; citation: 203)
  26. Koehl, W., Amin,S., Yamazaki, Hiroshi, Ueng, Yune-Fang, Tateishi T., Guengerich, F. Peter, Hecht, S. S.*, Metabolic Activation of Chrysene by Human Hepatic and Pulmonary Cytochrome P450 Enzymes. Polycyclic Arom. Compound., 10, 59-66, 1996. (SCI; citation: 4)
  27. Nakhgevany, R., Bonsu, O., Barber, J., Mabrouk, P. A., Ueng, Yune-Fang, Bell, L. Chastine, and Guengerich, F. Peter*, Preparation, purification, and spectrophotometric characterization of cytochrome P450 1A2 conjugated with polyethylene glycol monoethyl ether. Biochem. Biophys. Res. Comm. 222: 406-409, 1996. (SCI; citation: 4)
  28. Yamazaki, Hiroshi, Johnson, W. W., Ueng, Yune-Fang, Shimada, Tsutomu, and Guengerich, F. Peter*, Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. J. Biol. Chem. 271: 27438-27444, 1996. (SCI;IF= 4.573; citation: 173)
  29. Guengerich, F. Peter*, Ueng, Yune-Fang, Kim, B. R., Langouet, S., Coles, B., Iyer, R. S., Their, R., Harris, T. M., Shimada, Tsutomu, Yamazaki, Hiroshi, Ketterer, B., Guillouzo, A. Activation of toxic chemicals by cytochrome P450 enzymes: regio- and stereoselective oxidation of aflatoxin B1. Adv. Exp. Med. Biol. 387: 7-15, 1996. (SCI; IF= 1.958; citation: 8)
  30. Ueng, Yune-Fang, Kuwabara, Takashi, Chun, Young-Jin, and Guengerich, F. Peter*, Cooperativity in oxidations catalyzed by cytochrome P450 3A4. Biochemistry 36: 370-381, 1997. (SCI;IF=2.952; citation: 364)
  31. Johnson, W. W., Ueng, Yune-Fang, Mannervik, B., Hayes, J., Ketter, B., and Guengerich, F. Peter*, Conjugation of highly reactive aflatoxin B1 8,9-exo-epoxide catalyzed by rat and human glutathione S-transferase: estimation of kinetic parameters. Biochemistry 36: 3056-3060, 1997. (SCI;IF=2.952; citation: 70)
  32. Johnson, W. W., Yamazaki, Hiroshi, Shimada, Tsutyomu, Ueng, Yune-Fang, and Guengerich, F. Peter*, Aflatoxin B1 8,9-epoxide hydrolysis in the presence of rat and human epoxide hydrolase. Chem. Res. Toxicol. 10: 672-676, 1997. (SCI;IF: 3.278; citation: 51)
  33. Gillam, E. M. J., Wunsch, R. M., Ueng, Yune-Fang, Shimada, Tsutomu, Reilly, P. E. B., Kamataki, T., and Guengerich, F. Peter*, Expression of cytochrome P450 3A7 in Escherichia coli: effects of 5’ modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductase. Arch. Biochem. Biophys., 346: 81-90, 1997. (SCI;IF: 3.017; citation: 48)
  34. Guengerich, F. Peter*, Johnson, W. W., Shimada, Tsutomu, Ueng, Yune-Fang, Yamazaki, Hiroshi, and Langouet, S., Activation and detoxication of aflatoxin B1. Mutat. Res., 402: 121-128, 1998. (SCI;IF: 1.829; citation: 210)
  35. Ueng, Yune-Fang, Shimada, Tsutomu, Yamazaki, Hiroshi, and Guengerich, F. Peter*, Aflatoxin B1 oxidation by human cytochrome P450s. J. Toxicol. Sci., 23, Suppl. II, 132-135, 1998. (SCI;IF:1.436 citation: 4)
  36. Ueng, Yune-Fang*, The modulatory effects of flavones on human P450-catalyzed aflatoxin B1 oxidation. J Chin. Med., 9, 88-89, 1998. (non-SCI)
  37. Chen, Chien-Fu*, Ueng, Yune-Fang, Huang, C.-S., 肝毒及其解毒劑. J. Chin. Med. Pharmaceu. Res. 20, 15-24, 1999. (non-SCI)
  38. Ueng, Yune-Fang*, Chang, Yuh-Lih, Oda, Yoshimitsu, Park, San-Shin, Liao, Jyh-Fei, Lin, Min-Fang, and Chen, Chieh-Fu, In vitro and in vivo effect of naringin on cytochrome P450-dependent monooxygenase. Life Sci., 65, 2591-2602, 1999. (SCI;IF: 3.448; citation: 48)
  39. Ueng, Yune-Fang*, Shyu, Chi-Chuo, Lin, Yun-Lian, Liao, Jyh-Fei, and Chen, Chieh-Fu, Effects of baicalein and wogonin on drug-metabolizing enzymes in C57BL/6J mice. Life Sci. 67, 2189-2200, 2000. (SCI;IF: 3.448; citation: 39)
  40. Ueng, Yune-Fang*, Chen, Chien-Chih, and Chen, Chieh-Fu, Inhibition of benzo(a)pyrene hydroxylation by lignans isolated from Justicia procumbens. J. Food Drug Anal., 8, 309-314, 2000. (SCI; IF: 6.079; citation: 5)
  41. Ueng, Yune-Fang*, Shyu, Chi-Chuo, Liu, Tsung-Yun, Oda, Yoshimitsu, Lin, Yun-Lian, Liao, Jyh-Fei, and Chen, Chieh-Fu, Protective effects of baicalein and wogonin against benzo(a)pyrene and aflatoxin B1-induced genotoxicities. Biochem. Pharmacol. 62, 1653-1660, 2001. (SCI;IF: 4.852; citation: 31)
  42. Ueng, Yune-Fang*, Wang, J.-J., Lin, Lie-Chwen, Park, San-Shin, and Chen, Chieh-Fu, Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of herbal drug Evodia rutaecarpa. Life Sci., 70, 207-217, 2001. (SCI;IF: 3.448; citation: 34)
  43. Ueng, Yune-Fang*, Jan, Woan-Ching, Lin, Lie-Chwen, Chen, Ta-Liang, Guengerich, F. Peter, and Chen, Chieh-Fu, The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug Metab. Dispos., 30, 349-353, 2002. (SCI;IF: 3.354; citation: 64)
  44. Ueng, Yune-Fang* and Chen, Chieh-Fu, Effects of CVT-E002, a proprietary extract from the North American ginseng (Panax quiquefolium) on hepatic drug-metabolizing enzymes in C57BL/6J mice. J Chinese Med., 13, 89-96, 2002.
  45. Ueng, Yune-Fang*, Ko, Han-Chieh, Chen, Chieh-Fu, Wang, Jong-Jing, Chen, Kuo-Tung, Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice. Life Sci., 71, 1267-1277, 2002. (SCI;IF: 3.448; citation: 30)
  46. Ueng, Yune-Fang*, Don, Ming-Jaw, Peng, Hsiao-Chi, Wang, Shu-Yun, Wang, Jong-Jing, and Chen, Chieh-Fu, Effects of Wu-chu-yu-tang and its component herbs on drug-metabolizing enzymes. Jpn. J. Pharmacol. 89, 267-273, 2002. (SCI; IF:1.724; citation: 27)
  47. Chen, Chieh-Fu*, Chiou, W.-F., Chou, C.-J., Liao, J.-F., Lin, L.-C., Wang, G.-J., and Ueng, Yune-Fang, Pharmacological effects of Evodia rutaecarpa and its bioactive components. Chinese Pharm. J., 54, 419-435, 2002. (non-SCI, citation: 6)
  48. Lewis, D. F. V. *, Lake, B. G., Dickins, M., Ueng, Yune-Fang, and Goldfard, P. S. Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure. Xenobiotica, 33, 239-254, 2003. (IF: 1.902; citation: 29)
  49. Ueng, Yune-Fang*, Kuo, Ya-Hui, Peng, Hsiao-Chi, Chen, Ta-Liang, Jan, Woan-Ching, Guengerich, F. Peter, Lin, Yun Lian, A diterpene quinone tanshinone IIA selectively inhibited mouse and human cytochrome P450 1A2. Xenobiotica, 33, 603-613, 2003. (SCI;IF: 1.902; citation: 43)
  50. Don, Ming-Jaw, Lewis, David F. V., Wang, Shu-Yun, Tsai, Mei-Wen, and Ueng, Yune-Fang*, Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1. Bioorganic Med. Chem. Lett., 13, 2535-2538, 2003. (SCI;IF: 2.448; citation: 43)
  51. Ueng, Yune-Fang*, Shyu, C.-C., Liu, Tsung-Yun, Oda, Yoshimitsu, Park, San-Shin, Lin, Yun-Lian, and Chen, Chie-Fu, Protective effects of baicalein and wogonin against mutagen-induced genotoxicities. Oriental Foods and Herbs, Ho, C.-T., Lin, J.-K., Zheng, Q.-Y., Ed., ACS Symposium Series No. 859, pp. 104-112, 2003. (citation: 2)
  52. Ueng, Yune-Fang* and Wang, Shu-Yun, The herbal preparation Wu-chu-yu-tang enhances the excretion of the CYP1A2 substrate caffeine in mice. J. Chinese Med., 14, 175-181, 2003. (non-SCI)
  53. Ueng, Yune-Fang*, Kuo, Ya-Hui, Lin, Yun-Lian, and Chen, Chieh-Fu, Induction of CYP1A by a diterpene quinone tanshinone IIA isolated from a medicinal herb Salvia miltiorrhiza in C57BL/6J but not in DBA/2J mice. Life Sci., 74, 885-896, 2004. (SCI; IF: 3.448; citation: 41)
  54. Ueng, Yune-Fang* and Chen, Ruei-Ming, The role of cytochrome P450 in herb-drug interaction. Current Pharmacogenomics, 2, 209-218, 2004. (citation: 8)
  55. Lin, Anya M. Y. *, Yang, C. H., Ueng, Yune-Fang, Lay, Y. P., Luh, T.-Y., Chuo, C. K., and Ho, L. T. Differential effects of carboxyfullerene on MPP+/MPTP-induced neurotoxicity. Neurochem. Intl., 44, 99-105, 2004. (SCI;IF: 3.092; citation: 23)
  56. Ueng, Yune-Fang*, Hsieh, Chih-Hang, Don, Ming-Jaw, and Ho, Li-Kang, Identification of the main cytochrome P450 involved in safrole 1’-hydroxylation. Chem. Res. Toxicol.,17, 1151-1156, 2004. (SCI;IF: 3.274; citation: 39)
  57. Wu, Gong-Jhe, Tai, Yu-Ting, Chen, Ta-Liang, Lin, Li-Ling, Ueng, Yune-Fang and Chen, Ruei-Ming*, Propofol specifically inhibits mitochondrial membrane potential but not complex I NADH dehydrogenase activity thus reducing cellular ATP biosynthesis and migration of macrophages. Annal. New York Acad. Sci. 1042, 168-176, 2005. (SCI;IF: 4.706; citation: 30)
  58. Ueng, Yune-Fang*, Tsai, Tung-Hu, Don, Ming-Jaw, Chen, Ruei-Ming, and Chen, Ta-Liang, Alteration of the pharmacokinetics of theophylline by rutaecarpine, an alkaloid of the medicinal herb Evodia rutaecarpa. J. Pharm. Pharmacol. 57, 227-232, 2005. (SCI;IF:2.39; citation: 20)
  59. Chou, Yueh-Ching, Ueng, Yune-Fang*, Chou, Chia-Yu, and Tien, Jung-Hsiung, Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes. Life Sci., 77, 735-745, 2005. (SCI;IF: 3.448; citation: 7)
  60. Ueng, Yune-Fang*, Hsieh, Chih-Hang, and Don, Ming-Jaw, Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole. Food Chem. Toxicol., 43, 707-712, 2005. (SCI;IF: 3.778; citation: 24)
  61. Ueng, Yune-Fang, Yu, H.-J., Lee, C.-H., Peng, C., Jan, W.-C., Ho, L.-K., Chen, Chieh-Fu, and Don, Ming-Jaw*, Identification of the microsomal oxidation metabolites of rutaecarpine, a main active alkaloid of the medicinal herb Evodia rutaecarpa, J Chromatograph. A, 1076, 103-109, 2005. (SCI;IF: 3.981; citation: 27)
  62. Kuo, Ya-Huei, Lin, Yun-Lian, Don, Ming-Jaw, Chen, Ruei-Ming, and Ueng, Yune-Fang*, Induction of cytochrome P450-dependent monooxygenase by extracts of the medicinal herb Salvia miltiorrhiza. J. Pharm. Pharmacol. 58, 521-527, 2006. (SCI; IF=2.405; citation: 48)
  63. Jan, W.-C., Don, Ming-Jaw, Chen, Chieh-Fu, Ho, Li-Kang, and Ueng, Yune-Fang*, Characterization of mouse cytochrome P450-catalyzed oxidative metabolism of rutaecarpine, an alkaloid of the herbal medicine Evodia rutaecarpa. J. Food Drug. Analysis., 14, 159-165, 2006. (SCI;IF: 6.079)
  64. Ueng, Yune-Fang*, Jan, W.-C., Don, Ming-Jaw, Ho, Li-Kang, and Chen, Chieh-Fu, Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450s. Drug Metab. Dispos., 34, 821-827, 2006. (SCI;IF: 3.354; citation: 24)
  65. Ueng, Yune-Fang* and Wu, Tian-Shung, Effects of cinnamophilin on mouse hepatic drug-metabolizing enzymes in vitro and in vivo. J. Chinese Med., 17, 135-142, 2006.
  66. Tseng, Jen-C., Don, Ming-Jaw, Lewis, D. F. V., Wang, S.-Y., and Ueng, Yune-Fang*, Inhibition of CYP1 activity by 7,8-dehydrorutaecarpine and its methoxylated derivatives. J. Food Drug Anal. 15, 480-487, 2007. (SCI;IF: 6.079; citation: 4)
  67. Su, C.-R., Ueng, Yune-Fang, Dung, N. X., Reddy, V. B., and Wu, Tian-Shung*, Cytochrome P450 3A4 inhibitors and other constituents of Fibraurea tinctoria. J. Nat. Prod., 70, 1930-1933, 2007. (SCI;IF: 4.257; citation: 20)
  68. Lee, H.-L., Chang, L. W., Wu, J.-P., Ueng, Yune-Fang, Tsai, M.-H., Hsieh, D. P. H., and Lin, P. *, Enhancements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism and carcinogenic risk via NNK/Arsenic interaction. Toxicol. Appl. Pharmacol., 227, 108-114, 2008. (SCI;IF: 4.219; citation: 12; 29/93=31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  69. Wu, Gong-Jhe, Chen, Ta-Liang, Ueng, Yune-Fang, Chen, Ruei-Ming*, Ketamine inhibits tumor necrosis factor-alpha and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c-Jun N-terminal kinase phosphorylation and activator protein-1 activation. Toxicol. Appl. Pharmacol., 228, 105-113, 2008. (SCI;IF: 4.219; citation: 80; 29/93=31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  70. Chen, Ta-Liang, Chang, Chia-Chen, Lin, Yi-Liang, Ueng, Yune-Fang, and Chen, Ruei-Ming*, Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1b gene expression in lipopolysaccharide-stimulated murine macrophage-like Raw 264.7 cells. Toxicol. Appl. Pharmacol., 240, 15-25, 2009. (SCI;IF: 3.347; citation: 41)
  71. Pan, Wen-Chi, Chen, Ruei-Ming, Shen, Y.-C., Chen, Chien-Chih, and Ueng, Yune-Fang*, Suppressive effect of tobacco smoke extracts on oral P-glycoprotein function and its impact in smoke-induced insult to oral epidermal cells. Toxicol. Lett. 185, 116-123, 2009. (SCI;IF: 3.262 citation: 13)
  72. Chung, Y.-T., Hsieh, L.-L., Chen, I-H., Liao, C.-T., Liou, S.-H., Chi, Chin-Wen, Ueng, Yune-Fang, and Liu, Tsung-Yun*, Sulfotransferase 1A1 haplotypes associated with oral squamous cell carcinoma susceptibility in male Taiwanese. Carcinogenesis 30, 286–294, 2009. (SCI;IF: 5.105; citation: 11)
  73. Yen, Chia-Hung, Hung, Jung-Hsien, Ueng, Yune-Fang, Liu, Shih-Ping, Chen, Shih-Yin, Liu, Hsiao-Han, Chou, Teh-Ying, Tsai, Ting-Fen, Darbha, Ramalakshmi, Hsieh, Ling-Ling, and Chen, Yin-Ming Arthur*, Glycine N-methyltransferase affects the metabolism of aflatoxin B1 and blocks its carcinogenic effect. Toxicol. Appl. Pharmacol., 235, 296-304, 2009. (SCI;IF: 4.219; citation: 32; 29/93=31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  74. Ueng, Yune-Fang*, Chen, Chien-Chih, Tsai, C.-C., and Souček, Pavel, Differential inductive profiles of hepatic cytochrome P450s by the extracts of Sophora flavescens in male and female C57BL/6JNarl mice. J. Ethnopharmacol., 126, 437-446, 2009. (SCI;IF: 4.360; citation: 17)
  75. Chou, Yueh-Ching, Lin, M.-H., Chung, Y.-T., Liu, Tsung-Yun, Wang, Szu-Yu, Chau, Gar-Yang, Chi, Chin-Wen, Souček, Pavel, Krausz, Kristopher W., Gelboin, Harry V., Lee, Chen-Hsen and Ueng, Yune-Fang*, The oxidative metabolism of dimemorfan by human cytochrome P450 enzymes. J. Pharm. Sci., 99, 1063-1077, 2010. (SCI;IF: 3.197; citation: 11)
  76. Ueng, Yune-Fang*, Tsai, Ching-Chin, Lo, Wei-Shang, and Yun, Chul-Ho, Induction of hepatic cytochrome P450s by the herbal medicine, Sophora flavescens extract in rats: the impact on the elimination of theophylline. Drug Metab. Pharmacokinet., 25, 560-567, 2010. (SCI; IF: 3.614; citation: 10; 129/276=46.7%/Pharmacology & Pharmacy)
  77. Kondrova, E., Stopka, P., Boumendjel, A., Ueng, Yune-Fang, Gut, I., and Souček, Pavel*, New model system for testing of effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anticancer Drugs, 22, 176-184, 2011. (SCI;IF: 2.320; citation: 25)
  78. Ueng, Yune-Fang* and Lin, Yun-Lian, Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, Cyp2e1, and Cyp3a activities in C57BL/6JNarl mice. J. Chinese Med., 22, 143-152, 2011. (non SCI, citation: 2)
  79. Ueng, Yune-Fang*, Chen, Chien-Chih, Chung, Yu-Ting, Liu, Tsung-Yun, Chang, Yu-Ping, Lo, Wei-Shang, Murayama, Norie, Yamazaki, Hiroshi, Souček, Pavel, Chau, Gar-Ying, Chi, Chin-Wen, Chen, Ruei-Ming, and Li, Ding-Tzai, Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes, and in mice in vivo. Brit. J. Pharmacol., 163, 1250-1262, 2011. July Corrigendum:165, 2808, 2012. (SCI; IF: 8.740; citation: 25; 12/276= 4.3%/Pharmacology & Pharmacy)
  80. Lo, Wei-Shang, Lim, Yun-Ping, Chen, Chien-Chih, Hsu, Chih-Chien, Souček, Pavel, Yun, Chul-Ho, Xie, Wen, and Ueng, Yune-Fang*, A dual function of the furanocoumarin chalepensin in inhibiting Cyp2a and inducing Cyp2b in mice: the protein stabilization and receptor-mediated activation. Arch. Toxicol., 86, 1927-1938, 2012, Dec. (SCI;IF: 5.153; citation: 11; 16/93=17.2%/Toxicology)
  81. Ueng, Yune-Fang*, Chen, Chien-Chih, Yamazaki, Hiroshi, Kiyotani, Kazuma, Chang, Yu-Ping, Lo, Wei-Shang, Li, Ding-Tzai, and Tsai, Pei-Lun, Mechanism-based inhibition of CYP1A1 and CYP3A4 by the furanocoumarin chalepensin. Drug Metab. Pharmacokinet. 28, 229-238, 2013, Jun. (SCI; IF: 3.614; citation: 17; 129/276=46.7%/Pharmacology & Pharmacy)
  82.  Chou, Yueh-Ching, Wang, Yi-Kai, Charng, Min-Ji, and Ueng, Yune-Fang*, Determination of serum atorvastatin concentrations in lipid-controlling patients with and without myalgia syndrome. J. Food Drug Anal. 21,147-153, 2013, Jun. (SCI; IF: 6.079; citation: 19)
  83. Wang, Sheng-Fan, Chou, Yueh-Ching, Mazumder, Nirmal, Kao, Fu-Jen, Nagy, Leslie D., Guengerich, F. Peter, Huang, Cheng, Lee, Hsin-Chen, Lai, Ping-Shan, and Ueng, Yune-Fang*, 7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells. Biochem. Pharmacol., 86,548-560, 2013, Aug. (SCI; IF: 5.858; Citation: 36; 39/276=14.1%/Pharmacology & Pharmacy)
  84. Lo, Sheng-Nan, Chang, Yu-Ping, Tsai, Keng-Chang, Chang, Chia-Yu, Wu, Tian-Shung**, and Ueng, Yune-Fang*, Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: selectivity, kinetic characterization, and molecular modeling. Toxicol. Appl. Pharmacol., 272, 671-680, 2013. Nov. (SCI; IF:4.219; citation: 40; 29/93= 31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  85. Lee, Kuo-Huaa, Ueng, Yune-Fanga, Wu, C.-W., Chou, Yueh-Ching, Ng, Yee-Yung*, Yang, W.-C., The recommended dose of ertapenem poses a potential risk for central nervous system toxicity in hemodialysis patients – case reports and literature reviews. J. Clin. Pharm. Therapeut. 40, 240-244, doi: 10.1111/jcpt.12239, 2015, Apr. (SCI; IF: 2.167; citation: 27)
  86. Lo, Sheng-Nan, Shen, Chien-Chang, Chang, Chia-Yu, Tsai, Keng-Chang, Huang, Chiung-Chiao, Wu, Tian-Shung, and Ueng, Yune-Fang*, The effect of oxidation on berberine-mediated CYP1 inhibition: oxidation behavior and metabolite-mediated inhibition. Drug Metab. Dispos., 43, 1100-1107, 2015, July. (SCI; IF: 3.922; citation: 10; 115/276=41.7%/Pharmacology & Pharmacy)
  87. Ueng, Yune-Fang*, Chen, Chien-Chih, Huang, Yu-Ling, Lee, I-Jung, Yun, Chul-Ho, Chen, Yu-Hsuan, and Huang, Chiung-Chiao, Effects of aqueous extract of Ruta graveolens and its ingredients on cytochrome P450, uridine diphosphate (UDP)-glucuronosyltransferase, and reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H)-quinone oxidoreductase in mice. J. Food Drug Anal., 23, 516-528, 2015. Aug. (SCI; IF: 6.079; citation: 11)
  88. Lin, Li-Wei, Ueng, Yune-Fang, Tsai, Keng-Chang, Hsu, Hung-Ju, Shih, Chun-Chuan, and Chen, Wang-Chuan*, Investigation of Interaction between Shu-Gin-Hwai-Shen-tang and Anticoagulant Warfarin from the Perspective of Structural Biology., Taiwan Journal of Chinese Medicine (臺灣中醫醫學雜誌), 13(1), 1-12, 2015.
  89. Chang, Yu-Ping, Huang, Chiung-Chiao, Shen, Chien-Chang, Tsai, Keng-Chang, and Ueng, Yune-Fang*, Differential inhibition of CYP1-catalyzed regioselective hydroxylation of estradiol by berberine and its oxidative metabolites. Drug Metab. Pharmacokinet., 30, 374-383, 2015, Dec. (SCI; IF: 2.014; citation: 11; 129/276=46.7%/Pharmacology & Pharmacy)
  90. Wang, Sheng-Fan, Chen, Meng-Shian, Chou, Yueh-Ching, Ueng, Yune-Fang, Yin, Pen-Hui, Yeh, Tien-Shun, Lee, Hsin-Chen*, Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway. Oncotarget, 7(45), 74132-74151, 2016, Sep. (citation: 66)
  91. Ueng, Yune-Fang*, Lu, Chung-Kuang, Yang, Sien-Hung, Wang, Hong-Jaan, Huang, Chiung-Chiao, Potentiation of the anticoagulation effect of warfarin by the herbal remedy Shu-Jing-Hwo-Shiee-Tang in rats: the dosing regimen and pharmacokinetic interaction. Drug Metab. Pharmacokinet., 32, 85-91, 2017, Jan. (SCI; IF: 2.041; citation: 6; 230/279 = 82.4%/Pharmacology & Pharmacy)
  92. Chen, Pei-Chun, Tsai, Wei-Jern, Ueng, Yune-Fang, Tzeng, Tsai-Teng, Chen, Hsiang-Ling, Zhu, Pei-Ru, Huang, Chia-Hsiang, Shiao, Young-Ji, Li, Wen-Tai*. Neuroprotective and anti-neuroinflammatory effects of hydroxyl-functionalized stilbenes and 2-arylbenzo[b]furans. Journal of Medicinal Chemistry, 60(9), 4062–4073, doi: 10.1021/acs.jmedchem.7b00376, 2017, May. (SCI; IF: 8.039; citation: 21; 3/63=4.8%/Chemistry, Medicinal)
  93. Wang, Chun-Wei, Huang, Chiung-Chiao, Chou, Pei-Hsin, Chang, Yu-Ping, Wei, Shouzuo, Guengerich, F. Peter, Chou, Yueh-Ching, Wang, Sheng-Fan, Lai, Ping-Shan, Pavel Souček and Ueng, Yune-Fang*, 7-Ketocholesterol and 27-hydroxycholesterol decreased doxorubicin sensitivity in breast cancer cells: estrogenic activity and mTOR pathway. Oncotarget, 8, 66033-66050, 2017, Aug. (non-SCI) https://doi.org/10.18632/oncotarget.19789 (citation: 17)
  94. Lo, Sheng-Nan, Wang, Chun-Wei, Chen, Yueh-Shieh, Huang, Chiung-Chiao, Wu, Tian-Shung, Li, Lih-Ann, Lee, I-Jung, and Ueng, Yune-Fang*, Berberine activates aryl hydrocarbon receptor but suppress CYP1A1 induction through miR-21-3p stimulation in MCF-7 breast cancer cells. Molecules, 22, 1847, doi: 10.3390/molecules22111847, 2017, Nov. (SCI; IF: 4.927; citation: 22; 114/294 =38.8%/Biochemistry & Molecular Biology; 65/179=36.3%/Chemistry,Multidisciplinary) Open access
  95. Yang, Jin-Fu, Liu, Yue-Rong, Huang, Chiung-Chiao, and Ueng, Yune-Fang*, The time-dependent effects of St John’s wort on cytochrome P450, uridine diphosphate-glucuronosyltransferase, glutathione S-transferase, and NAD(P)H-quinone oxidoreductasein mice. J. Food Drug Anal., 26, 422-431, 2018, Jan. doi: http://dx.doi.org/10.1016/j.jfda.2017.01.004. (SCI; IF: 6.157; citation: 11; 45/279=16.1%/Pharmacology & Pharmacy)
  96. Souček, Pavel*, Vrana, David, Ueng, Yune-Fang, Wei, Shouzou, Kozevnikovova, Renata, Guengerich, Frederick Peter, Selective changes in cholesterol metabolite levels in plasma of breast cancer patients after tumor removal. Clin. Chem. Laboratory Med., 56(3):e78-e81, pii: /j/cclm.ahead-of-print/cclm-2017-0409/cclm-2017-0409.xml. doi: 10.1515/cclm-2017-0409, 2018, Feb. (SCI; IF: 8.49; citation: 5; 3/29 =10.3%/Medical Laboratory Technology)
  97. Wang, Hong-Jaan, Lu, Chung-Kuang, Chen, Wei-Ching, Chen, An-Chi, and Ueng, Yune-Fang*, Shenmai-Yin decreased the clearance of nifedipine in rats: the involvement of time-dependent inhibition of nifedipine oxidation. J. Food Drug Anal., 27, 284-294, 2019, Jan. ; Corrigendum: 28(3), 2020 (https://doi.org/10.38212/2224-6614.3169 )(SCI; IF: 6.157; citation: 5; 45/279 =16.1%/Pharmacology & Pharmacy; 27/144= 18.8%/ Food Science & Technology)
  98. Chao, Ta-Chung, Pan, Wen-Chi, Tsai, Yi-Fang, Chou, Yueh-Ching, Liu, Yu-Rong, Wang, Sheng-Fan, Chen, Ying-Jen, Souček, Pavel, Ueng, Yune-Fang*, Plasma endoxifen and 4-hydroxytamoxifen levels in CYP2D6(C100T) carrying breast cancer patients and association with serum cholesterol. Toxicol. Appl. Pharmacol. 378, 114619, 2019, Aug. doi: 10.1016/j.taap.2019.114619. [Epub ahead of print] (SCI; IF: 4.460; citation: 2; 29/93=31.2%/Toxicology; 96/276=34.8%/Pharmacology & Pharmacy)
  99. Ueng, Yune-Fanga, Hong-Jaan Wanga, Shiao Chi Wu, and Yee-Yung Ng*, A thrice weekly ertapenem is practical for hemodialysis patients. Antimicrobial Agents and Chemotherapy, 63, e01427-19, 1-7, 2019, Dec. doi: 10.1128/AAC.01427-19. (SCI; IF: 5.938; citation: 2; 51/279=18.3%/Pharmacology & Pharmacy; 35/137= 25.5%/Microbiology)
  100. Ngo, Tuan Hung, Tsai, Pei Chun, Ueng, Yune-Fang, Chi, Kai Hsien*, Cytotoxicity assessment of PM2.5 collected from specific anthropogenic activities in Taiwan. International Journal of Environmental Research and Public Health, 16, 5043; doi:10.3390/ijerph16245043, 2019, Dec. Corrigendum: 17(14): E4932, 2020 (SCI; IF: 4.614; citation: 5; 71/210 = 33.8%/Public, Environ & Occupational Health; 100/279= 35.8%/Environ Sci) Open access
  101. Kloudova-Spalenkova, Alzbeta, Ueng, Yune-Fang, Shouzuo, Wei, Kopeckova, Katerina, Guengerich, F. Peter and Souček, Pavel*, Plasma oxysterol levels in luminal subtype breast cancer patients are associated with clinical data. J. Steroid Biochem. Mol. Biol., 197, 105566, 2020 March. (SCI; IF: 5.011; citation: 16; 48/146= 32.9%/Endocrinol. & Metabolism; 110/297= 37.0%/Biochem. & Mol. Biol.)
  102. Huang, Chun-Teng, Tseng, Ling-Ming, Chen, Ji-Lin, Chu, Pei-Yi, Lee, Chia-Han, Huang, Chun-Teng, Wang, Wan-Lun, Lau, Ka-Yi, Tseng, Mei-Fang, Chang, Yuan-Ya, Chiang, Tzu-Yi, Ueng, Yune-Fang, Lee, Hsin-Chen, Dai, Ming-Shen, and Liu, Chun-Yu*, Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression. EBioMedicine 54, 102717, 2020, Apr. doi: https://doi.org/10.1016/j.ebiom.2020.102717 (SCI; IF: 11.205; citation: 18; 11/195 = 5.6%/Medicine, Research & Experimental) Open access
  103. Chiang, Tzu-Yi, Wang, Hong-Jaan, Wang, Yen-Cih, Tan, Elise Chia-Hui, Lee, I-Jung, Yun, Chul-Ho, and Ueng, Yune-Fang*, Effects of Shengmai San on key enzymes involved in hepatic and intestinal drug metabolism in rats. J. Ethnopharmacol., 271, 113914, Feb., 2021. (SCI; IF:5.4; citation: 7; 7/72= 9.7%/Chemistry, Medicinal; 4/43= 9.3%/Integrative & Complementary Medicine;)
  104. Wang, Hong-Jaan, Tan, Elise Chia-Hui, Chiang, Tzu-Yi, Chen, Wei-Ching, Shen, Chien-Chang, and Ueng, Yune-Fang*, Effect of repeated Shengmai-San administration on nifedipine pharmacokinetics and the risk/benefit under co-treatment. J. Food Drug Anal. 30, 111-127, March, 2022. (SCI; IF: 3.6; citation: 1; 45/279=16.1%/Pharmacology & Pharmacy; 27/144 = 18.8%/ Food Science & Technology)
  105. Pan, Shih Yu, Chi, Kai Hsien, Wang, Yen-Cih, Wei, Wen-Chi and Ueng, Yune-Fang, Sub-toxic events induced by truck speed-facilitated PM2.5 in A549 human lung cells: counteraction by epigallocatechin-3-gallate. Scientific Reports, 12, 15004, 2022, Aug. (SCIE; IF: 4.997; citation: 0; multidisciplinary sciences – SCIE, 19/74=25.7%) Open access
  106. Liang, Ren-Jong, Hsu, Shu-Hao, Chang, Tien-Yu, Chiang, Tzu-Yi, Wang, Hong-Jaan**, Ueng, Yune-Fang*, Metabolism-involved drug interactions with traditional Chinese medicines in cardiovascular diseases. J. Food Drug Anal., 30, 331-356, 2022, Sep. (SCI; IF: 3.6; citation: 0; 45/279=16.1%/Pharmacology & Pharmacy; 27/144=18.8%/ Food Science & Technology)
  107. Wang, Hong-Jaan, Chen, An-Chi, Chen, Hsin-Ying, Cheng, Hsin-Chung, Kao, Li-Ting, Lu, Chung-Kuang, Tsai, Keng-Chang, Lee, I-Jung and Ueng, Yune-Fang *, Identification of the perpetrator imperatorin in Xin-yi-san-theophylline interaction: observed and predicted herb-drug interaction in rats. J. Pharm. Pharmacol., 75, 1225-1236, 2023. (SCI; IF: 3.3; 117/361=32.4%/Pharmacology & Pharmacy)
  108. Kao, Li-Ting, Chen, An-Chi, Wang, Hong-Jaan, Wen, Yuan-Liang, Lu, Chung-Kuang, Liaw, Chia-Ching, Tsai, Keng-Chang, and Ueng, Yune-Fang*, Xin-yi-san contains potent human CYP1A2 inhibitors and its combined use with theophylline in treatment increases adverse risks in patients. Phytomedicine, 130, 155760, 2024. (SCI; IF:6.7; Chemistry, Medicinal: 6/72; Integrative & Complementary Medicine: 2/43) https://doi.org/10.1016/j.phymed.2024.155760
  109. Cheng, Jing-Jy, Wei, Wen-Chi, Chen, Chang-Chang, Shiao, Young-Ji, Huang, Nai-Kuei, Liao, Chiu-Hsun, Wu, Tzu-Hsien, Ueng, Yune-Fang*, Liu, Hui-Kang*, Mulberry leaf extract exhibits multiple anti-diabetic activities and alleviates dysglycemia, systemic inflammation, hepatic steatosis, and xenobiotic metabolism abnormalities in type 2 diabetic mice. J. Funct. Food., 2024, in press. (SCI; IF:3.8; Food Science & Technology: 56/173; Nutrition & Dietetics: 35/114)
  110. Ueng, Yune-Fang*, Yu, C.-S., Yen, I-A., Pan, W.-C., Lin, P., Li, L.-A., Yun, C.-H., and Chang, K.-W., Induction of cytochrome P450 1A by safrole in human oral epidermal cells. Manuscript in preparation.
  111. Ueng, Yune-Fang*, Pan, W.-C., and Chen, C.-C., Alterations of drug-metabolizing enzymes by tobacco smoke in oral cells. Manuscript in preparation.

*Corresponding author

**Co-corresponding author

aEqual contribution

 

Review articles, book chapters, and published reports of meetings:

  1. Guengerich, F. P.*, Shimada, T., Yamazaki, H., Mimura, M., Iyer, R. S., Raney, K. D., Ueng, Yune-Fang, Harris, T. M., Their, R., Taylor, J. B., Pemble, S. M., and Ketterer, B., Activation of procarcinogens by cytochrome P450 oxidation and glutathione S-transferase conjugation. Proceedings, 10th Int. Sympos. Microsomes Drug Oxidations (18-21 July, Toronto), pp. 192-194, 1994.
  2. Guengerich, F. P.*, Ueng, Yune-Fang, Kim, B.-R., Langouet, S., Coles, B., Iyer, R. S., Their, R., Harris, T. M., Shimada, T., Yamazaki, H., Ketterer, B., and Guillouzo, A., Activation of chemicals by cytochrome P450 enzymes: regio- and stereoselective oxidation of aflatoxin B1. Proceedings, Fifth International Sympos. Biological Reactive Intermediates (4-8 January, Munich), 1996.
  3. Guengerich, F. P.*, Johnson, W. W., Ueng, Yune-Fang, Yamazaki, H., and Shimada, T., Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer. Environ. Health Perspect., 104, 557-562, 1996.
  4. Guengerich, F. P., Johnson, W. W., Shimada, T., Ueng, Yune-Fang, Yamazaki, H., and Langouet, S., Activation and detoxication of aflatoxin B1. Mutat. Res., 402, 121-128, 1998.
  5. Ueng, Yune-Fang, Shimada, T., Yamazaki, H., and Guengerich, F. P.*, Aflatoxin B1 oxidation by human cytochrome P450s. Proceedings, The 1 st International Conference of Asian Society of Toxicology (29 June-2 July, Yokohama, Japan), J. Toxicol. Soci. 23, Suppl. II, 132-135, 1998.
  6. Ueng, Yune-Fang*, The modulatory effects of flavones on human P450-catalyzed aflatoxin B1 oxidation. J Chin. Med., 9, 88-89, 1998.
  7. Chen, C.-F.*, Ueng, Yune-Fang, Huang, C.-S., 肝毒及其解毒劑. J. Chin. Med. Pharmaceu. Res. 20, 15-24, 1999.
  8. Chen, C.-F.*, Chiou, W.-F., Chou, C.-J., Liao, J.-F., Lin, L.-C., Wang, G.-J., and Ueng, Yune-Fang, Pharmacological effects of Evodia rutaecarpa and its bioactive components. Chinese Pharm. J., 54, 419-435, 2002.
  9. Ueng, Yune-Fang*, Shyu, C.-C., Liu, T.-Y., Oda, Y., Park, S. S., Lin, Y.-L., and Chen, C-F., Protective effects of baicalein and wogonin against mutagen-induced genotoxicities. Oriental Foods and Herbs, Ho, C.-T., Lin, J.-K., Zheng, Q.-Y., Ed., ACS Symposium Series No. 859, pp. 104-112, 2003.
  10. Ueng, Yune-Fang* and Chen, R.-M., The role of cytochrome P450 in herb-drug interaction. Current Pharmacogenomics, 2, 209-218, 2004.
  11. Chen, C.-F.*, Chiou, W.-F., Shiao, Y.-J., and Ueng, Yune-Fang, Ch. 9, Effects of ginseng on memory and erection functions in “The chemistry, metabolism and biological activities of ginseng” (Ed. J.-T. Zhang) Chemical Ind. Press, Beijing, China, 2006.
  12. Ueng, Yune-Fang, 藥物交互作用的機制及個體差異: 從葡萄柚汁談起。Taiwan Pharma Boosting Ace (藥業會刊), Taipei Pharmaceutical Business Association (台北市西藥商業同業公會). 435, 14-16, 2018.

 

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