Research Fellow |
Special Professional Service
|
Assay
|
---|---|---|
Huang, Nai-Kuei | 1. Parkinson's disease 2. Sipinocerebellar ataxia type 2 and 3 diseases 3. Huntington's disease 4. Ischemia 5. Substance abuse-induced neurotoxicity |
1. cytotoxicity assay, behavioral performance
2. cytotoxicity assay, behavioral performance
3. cytotoxicity assay, behavioral performance
4. cytotoxicity assay
5. cytotoxicity assay, behavioral performance
|
Cheng, Jing-Jy | 1.Cancer 2.Trauma 3.Cardiovascular Disease | 1. Cancer cell cytotoxicity (SRB assay) & angiogenesis assay (Matrigel tube formation assay) 2. Matrigel tube formation assay & Migration assay 3. ATF3 promotor screen |
Shiao, Young-Ji |
1.Alzheimer's disease 2.Parkinson's disease 3.Epilepsy | 1.Neurontoxicity in primary rat cortical neuron culture 2.Activation of primary rat cortical glial cell culture 3.Drug activity evaluation in APP/PS1 transgenic mice |
Liu, Hui-Kang | 1. Diabetes and related complications 2. Metabolic syndrome 3. Comorbidity of diabetes and Alzheimer's disease | 1a. Multiple assays for measuring hypoglycemic activity. 1b. Glucose tolerance test; HOMA values, HbA1c% 2. Energy expediture and endorine hormome assays. Gut microbiome analysis. 3. Blood Biochemistry. |
Shen, Yuh-Chiang | 1.Ischemic Stroke & Neurodegeneration 2.Osteoarthritis 3.Neurogenesis Promotion | 1.Middle cerebral artery occlusion & OGD cellular model 2.MIA-induced cartilage lesions 3.Stem cells in SVZ&DGZ |
Chiou, Wen-Fei |
1. Ovariectomy-induced osteoporosis 2. Osteoarthritis-induced osteoporosis 3. Joint inflammation |
1. In vitro: (1) Osteoblast differentiation assay (ALP
activity, mineralization, osteoids measurement,
action mechanism); (2) Osteoclast differentiation assay (TRAP activity, bone resorption, MNC formation, actin polymerization, action mechanism); (3) Chondrocyte differentiation (Alcian blue assay); (4) macrophage activation (pro-inflammatory cytokines measurement)
2. In vivo: (1) bone mineral density, (2) trabecular microarchitecture 3D measurement, (3) histochemistry assay, (4) bone turn-over rate; (5) paw edema measurement
|
Chiou, Chun-Tang | 1. Cancer and cancer side effects 2. Infectious diseases (Japanese encephalitis, dengue fever, hepatitis C) | 1. Antiproliferation assay (SRB, MTT) 2. Tumor xenograft mouse model 3. Cancer-related fatigue mouse model 4. Hepatitis C virus replicon cell model 5. Virus culture and titer determination (Japanese encephalitis virus, dengue virus) |
Tsai, Keng-Chang | 1.Immuno-Oncology 2.Alzheimer's disease | 1. TCM antibody、Phage Display 2. BACE1 Inhibition (ELISA) 3. Drug design, peptide design, antibody design and small compound design |
Tsai, Wei-Jern | 1. Cardiovascular diseases | 1. Anti-platelet aggregation analysis |
Wei, Wen-Chi |
1. Breast cancer 2. Inflammatory bowel disease, IBD 3. Colon cancer and melanoma | 1. Cytokine production assay 2. Differentiation and functional assays for MDSCs and T cells 3. Assays for protein expression and signal transduction 4. CRISPR/Cas gene editing 5. Orthotopic and tumor-resection mouse mammary tumor models 6. Dextran sulfate sodium (DSS)-induced mouse colitis model |
Research Fellow | Safety Model | Assay |
Ueng, Yune-Fang |
1.Alterations of drug metabolism; 2.Genotoxicity | 1.Human cytochrome P450 activities; 2.Metabolic activities of mouse and rat liver microsomes and cytosols; 3.Genotoxicity |
Research Fellow |
Special Professional Service
|
Assay |
Lee, I-jung | 1.Botany 2.Biology resources 3.Herbarium management | 1.Morphological, Microscopy Identification, DNA Identification 2.Fieldwork, Resource Exploration, Scientific Investigation 3.Herbarium Specimens Production and Collect |
Kuo, Yao-Haur | 1. Studies on the bioactive constituents and quality analysis of herbal medicine 2. The development of herbal medicine for the curing cancer and metabolic sydrome |
1. The isolation of bioactive constituents
2. Qualitative and quantitative analysis of quality control
3. Spectroscopic analysis for the elucidation of chemical structures
4. The screening platform of anticancer
|
Lu, Mei-Kuang | 1. Glycobiology 2.Mass-produce of high quality medicinal plants and fungi with the integration of culturing system, chemical profiling and bio-active guided selection. | 1.Gel-filtration column chromatograohy, Size exclusion column chramatography 2. HPAEC 3. Fermentation 4. Plant tissue and cell culture |
Don, Ming-Jaw |
1.Oganic synthesis
2.Isolation and structure elucidation
3.Quality analysis of traditional Chinese medicine
|
1.Total synthesis, Synthesis of analogues 2.Column chromatography, Spectral analysis (NMR, MS etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
Huang, Yu-Ling | 1. Studies on the bioactive constituents of medicinal plants 2. Quality analysis of traditional Chinese medicine | 1.Column chromatography, Spectral analysis (NMR, MS etc.) 2.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
Shen, Chien-Chang | 1.Oganic synthesis 2.Isolation and structure elucidation 3.Quality analysis of traditional Chinese medicine | 1.Total synthesis, Synthesis of analogues 2.Column chromatography, Spectral analysis (NMR, MS etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
Lu, Chung-Kuang | 1. Natural productions isolation and elucidation 2. Quality control of botany drugs 3. cultural techniques of marine microbes and algae | 1.Column chromatography, Spectral analysis (NMR, MS etc.) 2.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS 3. Fermentation and photo-bioreactor |
Li, Wen-Tai | 1. Drug design and synthesis 2. Development of active components in botanicals 3. Quality analysis of botanical materials | 1.Synthesis & manufacturing of active components 2.Isolation and identification of natural compounds (column chromatographyand spectral analysis etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
Lin, Lie-Chwen |
1. Analysis and standardization of medicinal plants. 2. Studies on the bioactive ingredients of medicinal plants. 3. Research and development for the manufacturing process of target compounds. | 1.Sample preparation techniques. 2.Column separation techniques. 3.Qualitative and quantitative analysis. 4.Spectral Analysis. 5.Chemical structure elucidation. |
Chen, Chang-Chang |
1. Germplasm preservation and cultivation of Chinese materia medica. 2. Educational Herb Garden management. | 1.Tissue culture. 2.Cropping system. |
Sunny Jui-Shan, Lin |
1.Chinese Medical Physiology 2.Chinese Medical Pathology 3.Research of Chinese Medical Body Constitution 4.Clinical Trials of Integration of Chinese and Western Medicine | Clinical research and clinical trials |