Research Fellow
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Special Professional Service
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Assay
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1. Parkinson's disease
2. Sipinocerebellar ataxia type 2 and 3 diseases 3. Huntington's disease 4. Ischemia 5. Substance abuse-induced neurotoxicity |
1. cytotoxicity assay, behavioral performance
2. cytotoxicity assay, behavioral performance 3. cytotoxicity assay, behavioral performance 4. cytotoxicity assay 5. cytotoxicity assay, behavioral performance |
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1.Cancer
2.Trauma 3.Cardiovascular Disease |
1. Cancer cell cytotoxicity (SRB assay) & angiogenesis assay (Matrigel tube formation assay)
2. Matrigel tube formation assay & Migration assay 3. ATF3 promotor screen |
1.Alzheimer's disease
2.Parkinson's disease 3.Epilepsy |
1.Neurontoxicity in primary rat cortical neuron culture
2.Activation of primary rat cortical glial cell culture 3.Drug activity evaluation in APP/PS1 transgenic mice |
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1. Diabetes and related complications
2. Metabolic syndrome 3. Comorbidity of diabetes and Alzheimer's disease |
1a. Multiple assays for measuring hypoglycemic activity.
1b. Glucose tolerance test; HOMA values, HbA1c% 2. Energy expediture and endorine hormome assays. Gut microbiome analysis. 3. Blood Biochemistry. |
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1.Ischemic Stroke & Neurodegeneration
2.Osteoarthritis 3.Neurogenesis Promotion |
1.Middle cerebral artery occlusion & OGD cellular model
2.MIA-induced cartilage lesions 3.Stem cells in SVZ&DGZ |
1. Ovariectomy-induced osteoporosis
2. Osteoarthritis-induced osteoporosis 3. Joint inflammation |
1. In vitro: (1) Osteoblast differentiation assay (ALP
activity, mineralization, osteoids measurement, action mechanism); (2) Osteoclast differentiation assay (TRAP activity, bone resorption, MNC formation, actin polymerization, action mechanism); (3) Chondrocyte differentiation (Alcian blue assay); (4) macrophage activation (pro-inflammatory cytokines measurement) 2. In vivo: (1) bone mineral density, (2) trabecular microarchitecture 3D measurement, (3) histochemistry assay, (4) bone turn-over rate; (5) paw edema measurement |
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1. Cancer and cancer side effects
2. Infectious diseases (Japanese encephalitis, dengue fever, hepatitis C) |
1. Antiproliferation assay (SRB, MTT)
2. Tumor xenograft mouse model 3. Cancer-related fatigue mouse model 4. Hepatitis C virus replicon cell model 5. Virus culture and titer determination (Japanese encephalitis virus, dengue virus) |
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1.Immuno-Oncology
2.Alzheimer's disease |
1. TCM antibody、Phage Display
2. BACE1 Inhibition (ELISA) 3. Drug design, peptide design, antibody design and small compound design |
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1. Cardiovascular diseases
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1. Anti-platelet aggregation analysis
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1. Breast cancer
2. Inflammatory bowel disease, IBD 3. Colon cancer and melanoma |
1. Cytokine production assay
2. Differentiation and functional assays for MDSCs and T cells 3. Assays for protein expression and signal transduction 4. CRISPR/Cas gene editing 5. Orthotopic and tumor-resection mouse mammary tumor models 6. Dextran sulfate sodium (DSS)-induced mouse colitis model |
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Research Fellow
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Safety Model
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Assay
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1.Alterations of drug metabolism;
2.Genotoxicity |
1.Human cytochrome P450 activities;
2.Metabolic activities of mouse and rat liver microsomes and cytosols; 3.Genotoxicity |
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Research Fellow
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Special Professional Service
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Assay
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1.Botany
2.Biology resources 3.Herbarium management |
1.Morphological, Microscopy Identification, DNA Identification
2.Fieldwork, Resource Exploration, Scientific Investigation 3.Herbarium Specimens Production and Collect |
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1. Studies on the bioactive constituents and quality analysis of herbal medicine
2. The development of herbal medicine for the curing cancer and metabolic sydrome |
1. The isolation of bioactive constituents
2. Qualitative and quantitative analysis of quality control 3. Spectroscopic analysis for the elucidation of chemical structures 4. The screening platform of anticancer |
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1. Glycobiology
2.Mass-produce of high quality medicinal plants and fungi with the integration of culturing system, chemical profiling and bio-active guided selection. |
1.Gel-filtration column chromatograohy, Size exclusion column chramatography
2. HPAEC 3. Fermentation 4. Plant tissue and cell culture |
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1.Oganic synthesis
2.Isolation and structure elucidation 3.Quality analysis of traditional Chinese medicine |
1.Total synthesis, Synthesis of analogues
2.Column chromatography, Spectral analysis (NMR, MS etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
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1. Studies on the bioactive constituents of medicinal plants 2. Quality analysis of traditional Chinese medicine
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1.Column chromatography, Spectral analysis (NMR, MS etc.)
2.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
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1.Oganic synthesis
2.Isolation and structure elucidation 3.Quality analysis of traditional Chinese medicine |
1.Total synthesis, Synthesis of analogues
2.Column chromatography, Spectral analysis (NMR, MS etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
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1. Natural productions isolation and elucidation
2. Quality control of botany drugs 3. cultural techniques of marine microbes and algae |
1.Column chromatography, Spectral analysis (NMR, MS etc.)
2.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS 3. Fermentation and photo-bioreactor |
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1. Drug design and synthesis
2. Development of active components in botanicals 3. Quality analysis of botanical materials |
1.Synthesis & manufacturing of active components
2.Isolation and identification of natural compounds (column chromatographyand spectral analysis etc.) 3.HPLC, UPLC, GC/MS, LC/MS/MS, LC/HRMS |
1. Analysis and standardization of medicinal plants.
2. Studies on the bioactive ingredients of medicinal plants. 3. Research and development for the manufacturing process of target compounds. |
1.Sample preparation techniques.
2.Column separation techniques. 3.Qualitative and quantitative analysis. 4.Spectral Analysis. 5.Chemical structure elucidation. |
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1. Germplasm preservation and cultivation of Chinese materia medica.
2. Educational Herb Garden management. |
1.Tissue culture.
2.Cropping system. |
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1.Chinese Medical Physiology
2.Chinese Medical Pathology 3.Research of Chinese Medical Body Constitution 4.Clinical Trials of Integration of Chinese and Western Medicine |
Clinical research and clinical trials
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